BISProShares UltraShort Nasdaq Biotechnology
Seeks daily investment results that correspond to -2x the daily performance of the Nasdaq Biotechnology Index.
By ProShares · Launched 2010
0.95%
#4,882 of 5,861 · expensive
$2M
#5,469 of 5,861 · small
-53.3%
16 years
#753 of 5,861 · established
Performance
Total-return NAV · USDTotal-return NAV, USD. Net of fund fees, before tax.
What's inside
How Beacon categorizes this fundAsset class
EquityRegion
North americaStrategy
Inverse
Sector
Health careIndex tracked
Nasdaq Biotechnology Index
What it actually holds
By weightConcentration
synthetic exposure — holdings shown are derivatives collateral, not the fund's positions
Asset allocation
Risk profile
Last 12 months · Sharpe & Sortino need 3+ yearsYear-on-year price swings
Worst peak-to-trough loss
Listing
- Exchange
- NASDAQ Global Select Market
Full fund details
- Objective
- Seeks daily investment results that correspond to -2x the daily performance of the Nasdaq Biotechnology Index.
- Strategy
- Invests in derivatives to gain inverse leveraged exposure to the Nasdaq Biotechnology Index, which includes U.S. and non-U.S. biotechnology and pharmaceutical companies. The Fund aims for daily results that are two times the inverse of the Index's performance, rebalancing daily to maintain this target.
- Inception date
- April 6, 2010
- Fund family
- ProShares
Similar funds
Same asset class, closest by strategy & exposureOur take
Structural notes on how this fund behaves. Read our guide on the 6 warning signs.
You can be right and still lose
This fund returns the opposite of its benchmark's daily move, then resets. Hold it longer and the daily compounding takes over: the market can move your way over a week and you still finish down. It works as a one-day hedge and nothing beyond that.
Sources: Cheng & Madhavan, 'The Dynamics of Leveraged and Inverse ETFs' (2009)
Educational analysis of structural product characteristics. Not investment advice. Always read the fund prospectus and consult a qualified advisor before investing. More
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Data updated on 2026-08-04