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TMED vs XLVI

T. Rowe Price Health Care ETF vs State Street Health Care Select Sector SPDR Premium Income ETF

TMED

T. Rowe Price Health Care ETF

T. Rowe Price

Annual cost

0.44%

Fund size

$19M

XLVI

State Street Health Care Select Sector SPDR Premium Income ETF

State Street Investment Management

Annual cost

0.35%

Fund size

$14M

Key differences

  • XLVI costs 0.09% less per year.
  • TMED is classified as equity, while XLVI is alternative — different risk/return profiles.
  • TMED covers global markets; XLVI covers north america.
  • TMED follows a active selection strategy; XLVI uses option income.

Side-by-side comparison

TMEDXLVI
Annual cost (TER)0.44%0.35%
Fund size (AUM)$19M$14M
Since20252025
Dividend yield
Asset classequityalternative
Regionglobalnorth america
Strategyactive selectionoption income
CAGR 1YN/AN/A
CAGR 3YN/AN/A
CAGR 5YN/AN/A
Sharpe 3YN/AN/A
Volatility 1Y
Max drawdown-11.11%-8.15%

Green dot indicates the better value for that metric. Performance data is historical and does not predict future results.

Similar to TMED and XLVI